Published: 27 March, 2018 | Volume 2 - Issue 1 | Pages: 031-036
Semi-isolated heart preparation of Nauphoeta cinerea. Pharmacological effects of 200 µL addition of Nephrolepis exaltata aqueous extracts (n=4, each), in comparison to saline control (n=4). Note the irreversible blockade of heart beating with aqueous and diluted 1:1 and 1:2 extracts. Diluted 1:4 and 1:8 extracts showed declines of 35 % and 9 %, respectively at first 5 minutes, with subsequent recovery at 30 min with no statistical difference in comparison to saline control. *p<0.05, in comparison among groups and saline control. #p>0.05 (in 1:4 extract, compared to acetylcholine; 1:8 extract, compared to saline control). **p>0.05 compared to saline control.