Research Article

Quantification of minor, trace and toxic elements in stems of Santalum album (L.), Mangiferra indica (L.) and Tinospora cordifolia by instrumental neutron activation analysis

Garg AN*, Ruchi Singh, Maharia RS, Dutta RK and Arpita Datta

Published: 04 March, 2022 | Volume 6 - Issue 1 | Pages: 008-014

Stems of Santalum album (Sandalwood), Mangiferra indica (Mango wood), and Tinospora cordifolia (Giloy) are widely used in the preparation of herbal medicines and formulations in the traditional Indian health care system called Ayurveda. These were analyzed for 4 minor (K, Ca, Cl, Mg) and 13 traces (As, Ce, Co, Cr, Cu, Fe, Hg, La, Mn, Na, Se, V, and Zn) including toxic elements by instrumental neutron activation analysis (INAA). Samples in powder form along with reference materials (NIST SRM 1547 and INCT MPH-2) as comparators were irradiated for 1 min/6 h in Dhruva/CIRUS reactors at BARC, Mumbai. Gamma activity was measured by high-resolution gamma-ray spectrometry. In general, K, Ca, Fe, Mn, and Zn contents are very high in all the samples but Santalum album, widely used as a perfume, is more enriched in K, Ca, Cr, Zn, and Se. The concentration of Ca is always high as a major constituent (> 10 mg/g) in all the stem/bark of plant species. A strong inverse correlation (R2 = 0.9999) was observed between Fe and Zn in all three samples and that may be useful in drug manufacturing.

Read Full Article HTML DOI: 10.29328/journal.jpsp.1001067 Cite this Article Read Full Article PDF


Elemental analysis; INAA; Micronutrients; Santalum album; Mangiferra indica; Tinospora cordifolia; Ca content


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