Abstract

Mini Review

Advances in research of the structural gene characteristics of the aflatoxin biosynthetic gene cluster

Zhu-Mei He* and Qi-Zhang Li

Published: 31 October, 2018 | Volume 2 - Issue 3 | Pages: 068-082

Aflatoxins, produced by Aspergillus spp., are strongly toxic and carcinogenic fungal secondary metabolites. Aflatoxin biosynthesis is a complex process and involves at least 30 genes clustered within an approximately 75 kB gene cluster. In this paper, we reviewed current status of the researches on the characterized structural genes involved in aflatoxin biosynthesis and their roles in aflatoxin-producing fungi, especially in A. flavus and A. parasiticus, which will improve our understanding of the mechanism of aflatoxin biosynthesis and regulation and provide reference for further study.

Read Full Article HTML DOI: 10.29328/journal.jpsp.1001022 Cite this Article Read Full Article PDF

Keywords:

Aflatoxins; Structural genes; Aspergillus flavus; Aspergillus parasiticus; promoter

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